WebFeb 1, 2014 · CCS52 proteins generally block the mitotic programme and induce endocycle onset in plants [ 17, 18, 19, 20, 21, 22 ]. For instance, Arabidopsis ccs52a1 mutants exhibit delayed endocycle entry in roots caused by a decrease in APC/C activity and thus stabilisation of CYCA2;3 proteins [ 23]. WebTranscriptional repression of the APC/C activator CCS52A1 promotes active termination of cell growth Christian Breuer1, Kengo Morohashi2,3, Ayako Kawamura1, Naoki Takahashi4, Takashi Ishida1,4, Masaaki Umeda4, Erich Grotewold2,3 and Keiko Sugimoto1,* 1RIKEN Plant Science Center, Yokohama, Kanagawa, Japan, 2Center for Applied Plant …
Transcriptional repression of the APC/C activator CCS52A1 …
WebCCS52A1, a substrate-specific activator of the anaphase promoting complex/cyclosome (APC/C), is essential for the transition from mitosis to endoreduplication. Here, we show that DNA-binding with one finger (Dof) transcription factors directly regulate the transcription of the CCS52A1 gene. WebDec 1, 2010 · Loss of CCS52A1 function enhances the multi-cellular trichome phenotype in sim mutants whereas overexpression of either CCS52A1 or CCS52A2 rescues the sim trichome phenotypes. This genetic study shows that the combined functions of SIM and CCS52A1 down-regulate the level of CYCB/CDK complexes during the establishment of … tautuaa pba
Transcriptional Repression of the APC/C Activator Genes …
WebMED16 associates with the promoters of the Anaphase Promoting Complex/Cyclosome activators CELL CYCLE SWITCH52 A1 ( CCS52A1) and CCS52A2 (encoding important … WebCCS52A1 encodes a CDH1/FZR-like protein, a class of proteins that function as activators of the anaphase-promoting complex. Unicellular ccs52A1 trichomes become … WebUnicellular ccs52A1 trichomes become multicellular upon overexpression of B-type cyclin, consistent with repression of the accumulation of mitotic cyclins in the developing trichome by CCS52A1. As these M-phase-specific cyclins are known to accumulate in sim mutant trichomes, our data suggest that CCS52A1 and SIM cooperate in tautua arts